Nasal cytology in the diagnosis and treatment of sinusitis in atopic and nonatopic children

J Otolaryngol. 2006 Aug;35(4):255-60. doi: 10.2310/7070.2005.0048.

Abstract

Objectives: To investigate the value of nasal cytology in the diagnosis of sinusitis and follow-up of atopic and nonatopic children before and after treatment and to compare the nasal cytologic findings with the radiologic findings.

Design: Open randomized investigation.

Setting: Ministry of Health, Ankara Diskapi Children's Hospital.

Method: Fifty-five children with bronchial asthma and/or allergic rhinitis followed by the Allergy Department of the Ministry of Health, Ankara Diskapi Children's Education and Research Hospital and 35 control children were evaluated for the following parameters: symptoms and signs of sinusitis, total serum immunoglobulin E level and eosinophil count, skinprick tests to common allergens, paranasal sinus radiographs, and nasal cytology (by the Rhinoprobe [Synbiotics Inc. London] method and wax paper blow).

Main outcome measures: Nasal cytology, radiologic findings, and treatment.

Results: There were no significant correlations between radiologic and cytologic findings in any of the groups (p > .05). In both atopic and nonatopic chronic sinusitis patients, the Rhinoprobe method had results similar to the radiologic findings, and there was a significant relationship (p < .05).

Conclusions: Nasal cytology is still a diagnostic tool in the follow-up and evaluation of chronic sinusitis in atopic children but should not be considered an adequate alternative to sinus radiography.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adolescent
  • Asthma / complications
  • Chi-Square Distribution
  • Child
  • Child, Preschool
  • Cytodiagnosis
  • Female
  • Humans
  • Male
  • Nasal Mucosa / cytology*
  • Nasal Mucosa / pathology
  • Radiography
  • Rhinitis, Allergic, Perennial / complications
  • Rhinitis, Allergic, Seasonal / complications
  • Sinusitis / diagnosis*
  • Sinusitis / diagnostic imaging
  • Sinusitis / pathology