Tumour banks in pediatric oncology

Clin Transl Oncol. 2006 Dec;8(12):884-8. doi: 10.1007/s12094-006-0151-4.

Abstract

Introduction: The information offered by the new genomic and proteomic techniques will play a central role in our knowledge of cancer; but it is limited by the lack of available tissue samples. Cancer in children is a sum of infrequent diseases, so tumor banks are support tools for translational research, providing access to a sufficiently large series of samples, which would minimize the asymmetric effect of the diverse origin.

Material and methods: From 2003 a Molecular Pathology Network in Pediatric Solid Tumors Netwoks exists in Spain, and we are a part of it. Our aim was to create a pediatric tumor bank program and consensus documents about its use.

Results: Standard Operating Procedures for collection and transport of samples have been created.

Conclusions: Thinking about the fast progress in Molecular Biology and the low frequency in pediatric tumors, it is vital to consider the importance of a bio bank.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Infant, Newborn
  • Neoplasms / pathology*
  • Spain
  • Tissue Banks* / ethics
  • Tissue Banks* / legislation & jurisprudence
  • Tissue Banks* / organization & administration