Periodic heterogeneity is introduced in experiments with thin solution layers where downward propagating planar autocatalytic fronts are hydrodynamically unstable and cellular patterns develop. The evolution of fingers is greatly affected by the spatial heterogeneity when the wave number associated with it falls in the vicinity of the most unstable mode of the reference system with uniform thickness. The imposed heterogeneity will drive the instability by amplifying the modes with the matching wave numbers as indicated by the experimentally constructed dispersion curves.