The first direct numerical simulations of violent flame folding because of the flame-acoustic resonance are performed. Flame propagates in a tube from an open end to a closed one. Acoustic amplitude becomes extremely large when the acoustic mode between the flame and the closed tube end comes in resonance with intrinsic flame oscillations. The acoustic oscillations produce an effective acceleration field at the flame front leading to a strong Rayleigh-Taylor instability during every second half period of the oscillations. The Rayleigh-Taylor instability makes the flame front strongly corrugated with elongated jets of heavy fuel mixture penetrating the burnt gas and even with pockets of unburned matter separated from the flame front.