Hexosamine biosynthetic pathway flux and cardiomyopathy in type 2 diabetes mellitus. Focus on "Impact of type 2 diabetes and aging on cardiomyocyte function and O-linked N-acetylglucosamine levels in the heart"

Am J Physiol Cell Physiol. 2007 Apr;292(4):C1243-4. doi: 10.1152/ajpcell.00521.2006. Epub 2006 Dec 6.
No abstract available

Publication types

  • Comment
  • Editorial

MeSH terms

  • Acetylglucosamine / biosynthesis
  • Aging*
  • Animals
  • Biomechanical Phenomena
  • Calcium / physiology
  • Cardiomyopathies / etiology
  • Diabetes Mellitus, Type 2 / complications
  • Diabetes Mellitus, Type 2 / metabolism*
  • Diabetes Mellitus, Type 2 / physiopathology
  • Glycosylation
  • Hexosamines / biosynthesis*
  • Hyperglycemia / physiopathology
  • Myocardial Contraction
  • Myocardium / metabolism*
  • Myocytes, Cardiac / physiology*
  • N-Acetylglucosaminyltransferases / biosynthesis*
  • Rats

Substances

  • Hexosamines
  • N-Acetylglucosaminyltransferases
  • O-GlcNAc transferase
  • Calcium
  • Acetylglucosamine