Abstract
This paper reports the synthesis and photodynamic therapy (PDT) effect of a porphyrin derivative containing tyrosine phosphate, which promises a new, useful approach to develop PDT agents.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Cell Survival / drug effects
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Cell Survival / radiation effects
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Dose-Response Relationship, Drug
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Ethylamines / chemistry
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HeLa Cells
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Humans
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Light
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Molecular Structure
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Phosphoric Monoester Hydrolases / chemistry*
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Phosphoric Monoester Hydrolases / metabolism
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Phosphotyrosine / chemistry*
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Phosphotyrosine / metabolism
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Photochemotherapy / methods
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Photosensitizing Agents / chemistry*
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Photosensitizing Agents / metabolism
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Photosensitizing Agents / pharmacology
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Porphyrins / chemistry*
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Porphyrins / metabolism
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Porphyrins / pharmacology
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Protoporphyrins / chemistry
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Spectrophotometry
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Triazoles / chemistry
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Urea / analogs & derivatives
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Urea / chemistry
Substances
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Ethylamines
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Photosensitizing Agents
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Porphyrins
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Protoporphyrins
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Triazoles
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Phosphotyrosine
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N,N-diisopropylethylamine
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Urea
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Phosphoric Monoester Hydrolases
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2-(1H-benzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate