[Effectiveness of infliximab in patients with Behçet syndrome and severe uveoretinitis. Report of five cases]

Rev Med Chil. 2006 Jul;134(7):875-82. doi: 10.4067/s0034-98872006000700011. Epub 2006 Aug 29.
[Article in Spanish]

Abstract

The efficacy and safety of repeated administration of infliximab was evaluated in five patients (two men, three women) with Behçet syndrome accompanied by severe uveoretinitis. Ocular and extra ocular inflammation was suppressed in all patients during the observation period without any serious adverse reactions. The results in these patients suggests that TNF-á blockade is effective in patients with severe ocular Behçet syndrome.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / therapeutic use*
  • Antibodies, Monoclonal / therapeutic use*
  • Behcet Syndrome / diagnosis
  • Behcet Syndrome / drug therapy*
  • Female
  • Fluorescein Angiography
  • Humans
  • Infliximab
  • Male
  • Middle Aged
  • Retinitis / diagnosis
  • Retinitis / drug therapy*
  • Uveitis / diagnosis
  • Uveitis / drug therapy*
  • Visual Acuity

Substances

  • Anti-Inflammatory Agents
  • Antibodies, Monoclonal
  • Infliximab