Antimicrobial activity of volatile components and various extracts of the red alga Jania rubens

Phytother Res. 2007 Feb;21(2):153-6. doi: 10.1002/ptr.2045.

Abstract

The methanol, dichloromethane, hexane, chloroform and volatile oil extracts of the red alga Jania rubens were tested in vitro for their antimicrobial activity (five Gram-positive, four Gram-negative bacteria and Candida albicans ATCC 10239). GC-MS analysis of the volatile components of J. rubens identified 40 compounds which constituted 77.53% of the total. The volatile components of J. rubens consisted of n-docosane (6.35%), n-eicosane (5.77%) and n-tetratriacontane (5.58%) as major components. The methanol and chloroform extracts (4 mg/disc) showed more potent antimicrobial activity than the hexane and dichloromethane extracts and the volatile oil of J. rubens.

MeSH terms

  • Anti-Infective Agents / pharmacology*
  • Bacteria / drug effects
  • Candida albicans / drug effects
  • Complex Mixtures / pharmacology
  • Microbial Sensitivity Tests
  • Oils, Volatile / pharmacology*
  • Rhodophyta / chemistry*

Substances

  • Anti-Infective Agents
  • Complex Mixtures
  • Oils, Volatile