One new anthraquinone from marine Streptomyces sp. FX-58

Nat Prod Res. 2006 Nov;20(13):1207-10. doi: 10.1080/14786410600899142.

Abstract

One new anthraquinone, 1,8-dihydroxy-2-ethyl-3-methylanthraquinone (1), together with two known compounds octadecanoic acid (2) and cholest-4-en-3-one (3) was isolated from marine actinomycete Streptomyces sp. FX-58. The structure of 1 was elucidated on the basis of spectroscopic methods, especially, the 2D-NMR spectral analysis. The cytotoxic activities of 1 were evaluated in vitro.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthraquinones / chemistry
  • Anthraquinones / isolation & purification*
  • Anthraquinones / pharmacology
  • Chenopodiaceae / microbiology*
  • China
  • Cytotoxins / chemistry
  • Cytotoxins / isolation & purification*
  • Cytotoxins / pharmacology
  • Formazans / chemistry
  • HL-60 Cells
  • Humans
  • Inhibitory Concentration 50
  • Mass Spectrometry
  • Molecular Structure
  • Nuclear Magnetic Resonance, Biomolecular
  • Spectrophotometry, Ultraviolet
  • Streptomyces / chemistry*
  • Tetrazolium Salts / chemistry

Substances

  • Anthraquinones
  • Cytotoxins
  • Formazans
  • Tetrazolium Salts
  • MTT formazan