Abstract
One new anthraquinone, 1,8-dihydroxy-2-ethyl-3-methylanthraquinone (1), together with two known compounds octadecanoic acid (2) and cholest-4-en-3-one (3) was isolated from marine actinomycete Streptomyces sp. FX-58. The structure of 1 was elucidated on the basis of spectroscopic methods, especially, the 2D-NMR spectral analysis. The cytotoxic activities of 1 were evaluated in vitro.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Anthraquinones / chemistry
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Anthraquinones / isolation & purification*
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Anthraquinones / pharmacology
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Chenopodiaceae / microbiology*
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China
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Cytotoxins / chemistry
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Cytotoxins / isolation & purification*
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Cytotoxins / pharmacology
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Formazans / chemistry
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HL-60 Cells
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Humans
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Inhibitory Concentration 50
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Mass Spectrometry
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Molecular Structure
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Nuclear Magnetic Resonance, Biomolecular
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Spectrophotometry, Ultraviolet
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Streptomyces / chemistry*
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Tetrazolium Salts / chemistry
Substances
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Anthraquinones
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Cytotoxins
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Formazans
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Tetrazolium Salts
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MTT formazan