First report of occurrence of choroid plexus papilloma and medulloblastoma in the same patient

Childs Nerv Syst. 2007 May;23(5):587-9. doi: 10.1007/s00381-006-0249-6. Epub 2006 Nov 15.

Abstract

Introduction: Choroid plexus papilloma is a benign epithelial brain tumour showing a striking predilection for infants and occurring most frequently in the lateral and fourth ventricles. Medulloblastoma, on the other hand, is a primitive neuroectodermal tumour and is the most frequent malignant brain tumour of the posterior fossa in children. In this study, we report a metachronous occurrence of choroid plexus papilloma and medulloblastoma in the same patient, which has not been reported before to the best of our knowledge.

Case report: The authors describe the case of a girl who presented with an atypical choroid plexus papilloma on the posterior wall of the left lateral ventricle at 3 months of age that was resected completely. She was followed up regularly after surgery and made good progress with normal development. At 8 years of age, she presented with right cerebellar medulloblastoma.

Discussion: The authors review literature for incidence and aetiology of the two tumours.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Cerebellar Neoplasms / complications
  • Cerebellar Neoplasms / pathology*
  • Cerebellar Neoplasms / surgery
  • Cerebral Ventricle Neoplasms / complications
  • Cerebral Ventricle Neoplasms / pathology*
  • Cerebral Ventricle Neoplasms / surgery
  • Craniotomy
  • Female
  • Humans
  • Hydrocephalus / complications
  • Infant
  • Medulloblastoma / complications
  • Medulloblastoma / pathology*
  • Medulloblastoma / surgery
  • Neurosurgical Procedures
  • Papilloma, Choroid Plexus / complications
  • Papilloma, Choroid Plexus / pathology*
  • Papilloma, Choroid Plexus / surgery
  • Third Ventricle / pathology
  • Third Ventricle / surgery

Substances

  • Antineoplastic Agents