Polyunsaturated fatty acids and neurological diseases

Mini Rev Med Chem. 2006 Nov;6(11):1201-11. doi: 10.2174/138955706778742740.

Abstract

This review summarizes the knowledge of the role of dietary PUFAs, especially omega-3, on normal brain function. Furthermore, it reports the evidence pointing to potential mechanisms of omega-3 fatty acids in development of neurological disorders and efficacy of their supplementation in terms of symptom management.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / drug effects
  • Brain / metabolism
  • Disease Progression
  • Fatty Acids, Unsaturated / chemistry
  • Fatty Acids, Unsaturated / deficiency*
  • Fatty Acids, Unsaturated / metabolism*
  • Fatty Acids, Unsaturated / pharmacology
  • Humans
  • Multiple Sclerosis / metabolism
  • Multiple Sclerosis / pathology
  • Nervous System Diseases / metabolism*
  • Nervous System Diseases / pathology

Substances

  • Fatty Acids, Unsaturated