Abstract
The evaluation of the biological and epidemiological properties of Ebola, Marburg, Lassa, and Machupo viruses suggests that they are of social importance for health care authorities. The studies have created prerequisites to the development of reliable biosafety means against these pathogens. Particular emphasis is laid on the methods for infection diagnosis and on the studies to design specific protective agents--immunoglobulins and inactivated vaccines.
MeSH terms
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Animals
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Antibody Specificity / immunology
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Antigens, Viral / administration & dosage
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Antiviral Agents / therapeutic use
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Arenaviruses, New World / immunology
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Arenaviruses, New World / pathogenicity*
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Disease Outbreaks*
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Ebolavirus / immunology
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Ebolavirus / pathogenicity*
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Global Health
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Hemorrhagic Fever, American* / epidemiology
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Hemorrhagic Fever, American* / pathology
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Hemorrhagic Fever, American* / therapy
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Hemorrhagic Fevers, Viral* / epidemiology
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Hemorrhagic Fevers, Viral* / pathology
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Hemorrhagic Fevers, Viral* / therapy
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Horses
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Humans
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Immunization
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Immunoglobulins / immunology
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Immunoglobulins / therapeutic use
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Laboratory Infection / epidemiology
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Lassa virus / immunology
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Lassa virus / pathogenicity*
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Marburgvirus / immunology
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Marburgvirus / pathogenicity*
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Ribavirin / therapeutic use
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Viral Vaccines / administration & dosage
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Virulence
Substances
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Antigens, Viral
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Antiviral Agents
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Immunoglobulins
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Viral Vaccines
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Ribavirin