Antidepressant-like activity of the Gastrodia elata ethanol extract in mice

Ben Hong Zhou; Xiao Jun Li; Min Liu; Zhenhua Wu; Xian Ming Hu

doi:10.1016/j.fitote.2006.06.016

Antidepressant-like activity of the Gastrodia elata ethanol extract in mice

Fitoterapia. 2006 Dec;77(7-8):592-4. doi: 10.1016/j.fitote.2006.06.016. Epub 2006 Sep 22.

Authors

Ben Hong Zhou¹, Xiao Jun Li, Min Liu, Zhenhua Wu, Xian Ming Hu

Affiliation

¹ The Renmin Hospital of Wuhan University, 238 Ziyang road, Wuhan City, Hubei Province, China.

PMID: 17052862
DOI: 10.1016/j.fitote.2006.06.016

Abstract

The hydroalcoholic extract of Gastrodia elata was evaluated for the antidepressant-like activity by means of behavioral models that included forced swimming, tail suspending and open-field tests. According to the results, G. elata extract is effective as an antidepressant drug.

MeSH terms

Administration, Oral
Animals
Antidepressive Agents / administration & dosage
Antidepressive Agents / pharmacology*
Antidepressive Agents / therapeutic use
Behavior, Animal / drug effects*
Depression / drug therapy
Dose-Response Relationship, Drug
Gastrodia*
Male
Maze Learning
Mice
Phytotherapy*
Plant Extracts / administration & dosage
Plant Extracts / pharmacology*
Plant Extracts / therapeutic use
Plant Roots
Swimming

Substances

Antidepressive Agents
Plant Extracts