[Advances on phytoestrogen intervening breast cancer]

Zhongguo Zhong Yao Za Zhi. 2006 Jun;31(12):957-60.
[Article in Chinese]

Abstract

Phytoestrogen is the bioactive substance from plant, with structure is very simliar to that of estrogen. Phytoestrogen is mainly comprises of isoflavone, lignan and coumarin. Epidemiological restrarch shows that the increasing the uptake phytoestrogen of can reduce the morbidities of breast and other cancers. In this paper, the food source, characteristic and relevant researches both in vitro and in vivo were reviewed, and its mechanisms of intervening breast cancer were also discussed.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Antioxidants / pharmacology
  • Apoptosis / drug effects*
  • Breast Neoplasms / enzymology
  • Breast Neoplasms / pathology*
  • Cell Line, Tumor
  • Coumarins / pharmacology
  • DNA Topoisomerases, Type II / metabolism
  • Female
  • Humans
  • Isoflavones / pharmacology
  • Lignans / pharmacology
  • Phytoestrogens / isolation & purification
  • Phytoestrogens / pharmacology*
  • Plants, Medicinal* / chemistry
  • Protein-Tyrosine Kinases / metabolism

Substances

  • Antioxidants
  • Coumarins
  • Isoflavones
  • Lignans
  • Phytoestrogens
  • Protein-Tyrosine Kinases
  • DNA Topoisomerases, Type II