Abstract
Visceral involvement in absence of lymphadenopathy is a rare manifestation in cat scratch disease; hepatic granulomas are rare, representing 0.3% of systemic manifestations of cat scratch disease, and gallbladder extension is a singular case. The present article refers to 2 rare cases of visceral cat scratch disease in immunocompetent adults with hepatic granulomatous inflammation, caused by Bartonella henselae infection, with gallbladder involvement in 1 case and no lymphadenopathy. Histological features demonstrated the presence of inflammatory necrotizing granulomatous nonneoplastic process. Molecular studies (polymerase chain reaction) were performed to confirm the infectious etiology.
MeSH terms
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Antigens, CD / genetics
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Antigens, CD / metabolism
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Antigens, CD34 / genetics
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Antigens, CD34 / metabolism
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Antigens, Differentiation, Myelomonocytic / genetics
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Antigens, Differentiation, Myelomonocytic / metabolism
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Bartonella henselae / genetics
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Bartonella henselae / pathogenicity*
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Cat-Scratch Disease / complications*
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Cat-Scratch Disease / immunology
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Cat-Scratch Disease / pathology*
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DNA, Bacterial / genetics
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Female
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Granuloma / etiology*
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Granuloma / immunology
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Granuloma / microbiology
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Granuloma / pathology
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Humans
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Immunocompetence*
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Liver / metabolism
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Liver / microbiology
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Liver / pathology
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Liver Diseases / etiology*
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Liver Diseases / immunology
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Liver Diseases / microbiology
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Liver Diseases / pathology
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Polymerase Chain Reaction
Substances
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Antigens, CD
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Antigens, CD34
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Antigens, Differentiation, Myelomonocytic
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CD68 antigen, human
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DNA, Bacterial