Molecular evolution of the H-NS protein: interaction with Hha-like proteins is restricted to enterobacteriaceae

J Bacteriol. 2007 Jan;189(1):265-8. doi: 10.1128/JB.01124-06. Epub 2006 Oct 13.

Abstract

We show here that chromosomal hha-like genes are restricted to the Enterobacteriaceae. The H-NS N-terminal domain of members of this family includes an unaltered seven-amino-acid sequence located between helixes 1 and 2, termed the Hha signature, that contains key residues for H-NS-Hha interaction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • DNA-Binding Proteins / genetics*
  • DNA-Binding Proteins / metabolism
  • Enterobacteriaceae / genetics*
  • Escherichia coli Proteins / metabolism
  • Evolution, Molecular
  • Molecular Sequence Data
  • Phylogeny
  • Sequence Alignment
  • Species Specificity

Substances

  • Bacterial Proteins
  • DNA-Binding Proteins
  • Escherichia coli Proteins
  • H-NS protein, bacteria
  • hha protein, E coli