[Prevention of osteoporosis by foods and dietary supplements. "Mainichi Hone Kea MBP": A foods for specified health uses (FOSHU) product containing MBP that has an effect to increase bone density]

Clin Calcium. 2006 Oct;16(10):1701-5.
[Article in Japanese]

Abstract

"Mainichi Hone Kea MBP" is a foods for specified health uses (FOSHU) product. It has been approved to write the next claim, "This product is suitable for those who care about bone health, because it contains MBP that has an effect to increase bone density", on this product. MBP is a complex of protein with a basic isoelectric point in milk protein. It has been shown that MBP promotes bone formation, suppresses bone resorption, increases bone mineral density, and increases bone strength in in vitro and in vivo studies. And, we also examined the effect of MBP in healthy adult women from twenties to fifties. A beverage containing MBP or a placebo beverage without MBP was given to volunteers for six months. The percentage increase of radial bone density was significantly higher in the MBP group than in the placebo group. This result has confirmed that MBP contributes to increased bone density in humans. To sum up, we believe that MAINICHI HONE KEA MBP, which contains MBP that has an effect to increase bone density, contributes to bone health.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adult
  • Bone Density / drug effects*
  • Female
  • Food, Organic* / analysis
  • Humans
  • In Vitro Techniques
  • Middle Aged
  • Milk Proteins / analysis
  • Milk Proteins / pharmacology*
  • Whey Proteins

Substances

  • Milk Proteins
  • Whey Proteins