Abstract
The relationship between endothelial dysfunction and stroke subtypes is unclear. We prospectively measured brachial flow-mediated vasodilation (FMD) in 143 patients with acute ischemic stroke and 40 controls. The overall stroke patients had impaired FMD, but only lacunar infarction had significantly impaired FMD vs the controls. Impaired FMD was an independent predictor for lacunar infarction. Ischemic stroke is associated with endothelial dysfunction, which is more conspicuous in lacunar infarction.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Aged
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Atherosclerosis / diagnostic imaging
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Atherosclerosis / physiopathology
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Blood Flow Velocity / physiology
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Blood Pressure / physiology
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Brachial Artery / diagnostic imaging
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Brachial Artery / physiopathology*
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Brain Infarction / diagnostic imaging
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Brain Infarction / physiopathology
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Cardiovascular Diseases
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Case-Control Studies
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Endothelium, Vascular / diagnostic imaging
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Female
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Humans
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Male
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Middle Aged
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Prospective Studies
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Regional Blood Flow / physiology*
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Retrospective Studies
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Stroke / classification
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Stroke / diagnostic imaging
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Stroke / pathology*
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Stroke / physiopathology*
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Ultrasonography / methods
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Vasodilation / physiology*