Phytochemical constituents from Salsola tetrandra

J Nat Prod. 2006 Sep;69(9):1366-9. doi: 10.1021/np060222w.

Abstract

The new norisoprenoid 3beta-hydroxy-5alpha,6alpha-epoxy-beta-ionone-2alpha-O-beta-d-glucopyranoside (1) and the long-chain hydroxy fatty acids 9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid (2) and 9,12,13-trihydroxyoctadeca-10(E)-dienoic acid (3) were isolated from Salsola tetrandra aerial parts, together with 3,4,5-trimethoxyphenyl-beta-d-glucopyranoside (4), 9-hydroxylinaloyl glucoside (5), taxiphyllin (6), trans-N-feruloyltyramine (7), and S-(-)-trans-N-feruloyloctopamine (8). Their structures were elucidated by extensive spectroscopic analysis and chemical methods. Compounds 6 and 8 displayed mild antibacterial activity against Staphylococcus aureus, whereas compound 6 showed the highest activity in the Artemia salina bioassay.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / isolation & purification*
  • Anti-Bacterial Agents / pharmacology
  • Escherichia coli / drug effects
  • Glucosides
  • Hydroxy Acids / chemistry
  • Hydroxy Acids / isolation & purification*
  • Hydroxy Acids / pharmacology
  • Microbial Sensitivity Tests
  • Micrococcus luteus / drug effects
  • Molecular Structure
  • Norisoprenoids
  • Nuclear Magnetic Resonance, Biomolecular
  • Oleic Acids / chemistry
  • Oleic Acids / isolation & purification*
  • Oleic Acids / pharmacology
  • Plants, Medicinal / chemistry*
  • Pseudomonas aeruginosa / drug effects
  • Salsola / chemistry*
  • Staphylococcus / drug effects
  • Tunisia

Substances

  • 3beta-hydroxy-5alpha,6alpha-epoxy-beta-ionone-2alpha-O-beta-D-glucopyranoside
  • 9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid
  • Anti-Bacterial Agents
  • Glucosides
  • Hydroxy Acids
  • Norisoprenoids
  • Oleic Acids
  • 9,12,13-trihydroxy-10-octadecenoic acid