Abstract
The new norisoprenoid 3beta-hydroxy-5alpha,6alpha-epoxy-beta-ionone-2alpha-O-beta-d-glucopyranoside (1) and the long-chain hydroxy fatty acids 9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid (2) and 9,12,13-trihydroxyoctadeca-10(E)-dienoic acid (3) were isolated from Salsola tetrandra aerial parts, together with 3,4,5-trimethoxyphenyl-beta-d-glucopyranoside (4), 9-hydroxylinaloyl glucoside (5), taxiphyllin (6), trans-N-feruloyltyramine (7), and S-(-)-trans-N-feruloyloctopamine (8). Their structures were elucidated by extensive spectroscopic analysis and chemical methods. Compounds 6 and 8 displayed mild antibacterial activity against Staphylococcus aureus, whereas compound 6 showed the highest activity in the Artemia salina bioassay.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Anti-Bacterial Agents / chemistry
-
Anti-Bacterial Agents / isolation & purification*
-
Anti-Bacterial Agents / pharmacology
-
Escherichia coli / drug effects
-
Glucosides
-
Hydroxy Acids / chemistry
-
Hydroxy Acids / isolation & purification*
-
Hydroxy Acids / pharmacology
-
Microbial Sensitivity Tests
-
Micrococcus luteus / drug effects
-
Molecular Structure
-
Norisoprenoids
-
Nuclear Magnetic Resonance, Biomolecular
-
Oleic Acids / chemistry
-
Oleic Acids / isolation & purification*
-
Oleic Acids / pharmacology
-
Plants, Medicinal / chemistry*
-
Pseudomonas aeruginosa / drug effects
-
Salsola / chemistry*
-
Staphylococcus / drug effects
-
Tunisia
Substances
-
3beta-hydroxy-5alpha,6alpha-epoxy-beta-ionone-2alpha-O-beta-D-glucopyranoside
-
9,12,13-trihydroxyoctadeca-10(E),15(Z)-dienoic acid
-
Anti-Bacterial Agents
-
Glucosides
-
Hydroxy Acids
-
Norisoprenoids
-
Oleic Acids
-
9,12,13-trihydroxy-10-octadecenoic acid