Investigation of reactivity and selectivity of DNA-alkylating duocarmycin analogues by high-resolution mass spectrometry

Angew Chem Int Ed Engl. 2006 Oct 6;45(39):6570-4. doi: 10.1002/anie.200600935.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkylating Agents / chemical synthesis*
  • Alkylating Agents / chemistry*
  • Cell Survival / drug effects
  • Crystallography, X-Ray
  • DNA / chemistry*
  • DNA Fragmentation
  • Duocarmycins
  • Electrophoresis, Polyacrylamide Gel
  • Indicators and Reagents
  • Indoles / chemical synthesis*
  • Indoles / chemistry*
  • Magnetic Resonance Spectroscopy
  • Mass Spectrometry
  • Prodrugs / chemical synthesis
  • Pyrroles / chemical synthesis
  • Pyrroles / chemistry
  • Spectrometry, Mass, Electrospray Ionization

Substances

  • Alkylating Agents
  • Duocarmycins
  • Indicators and Reagents
  • Indoles
  • Prodrugs
  • Pyrroles
  • duocarmycin SA
  • DNA