Novel conserved assembly factor of the bacterial flagellum

Björn Titz; Seesandra V Rajagopala; Claudia Ester; Roman Häuser; Peter Uetz

doi:10.1128/JB.00820-06

Novel conserved assembly factor of the bacterial flagellum

J Bacteriol. 2006 Nov;188(21):7700-6. doi: 10.1128/JB.00820-06. Epub 2006 Aug 25.

Authors

Björn Titz¹, Seesandra V Rajagopala, Claudia Ester, Roman Häuser, Peter Uetz

Affiliation

¹ Institute of Genetics, Forschungszentrum Karlsruhe, Box 3640, D-76021 Karlsruhe, Germany.

Abstract

TP0658 (FliW) and its orthologs, conserved proteins of unknown function in Treponema pallidum and other species, interact with a C-terminal region of flagellin (FlaB1-3 in T. pallidum; FliC in most other species). Mutants of orthologs in Bacillus subtilis and Campylobacter jejuni (yviF, CJ1075) showed strongly reduced motility. TP0658 stabilizes flagellin in a way similar to FliS, suggesting that TP0658 is a conserved assembly factor for the bacterial flagellum.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Bacillus subtilis / genetics
Bacillus subtilis / physiology
Bacterial Proteins / genetics
Bacterial Proteins / physiology*
Campylobacter jejuni / genetics
Campylobacter jejuni / physiology
Flagella / genetics
Flagella / physiology*
Flagellin / metabolism*
Movement
Treponema pallidum / genetics
Treponema pallidum / physiology*
Treponema pallidum / ultrastructure

Substances

Bacterial Proteins
Flagellin