Cucurbitane-type triterpenoids from Momordica charantia

Chi-I Chang; Chiy-Rong Chen; Yun-Wen Liao; Hsueh-Ling Cheng; Yo-Chia Chen; Chang-Hung Chou

doi:10.1021/np068008v

Cucurbitane-type triterpenoids from Momordica charantia

J Nat Prod. 2006 Aug;69(8):1168-71. doi: 10.1021/np068008v.

Authors

Chi-I Chang¹, Chiy-Rong Chen, Yun-Wen Liao, Hsueh-Ling Cheng, Yo-Chia Chen, Chang-Hung Chou

Affiliation

¹ Graduate Institute of Biotechnology, National Pingtung University of Science and Technology, Pingtung 912, Taiwan, Republic of China.

PMID: 16933869
DOI: 10.1021/np068008v

Abstract

Five new cucurbitane-type triterpenes, (23E)-25-methoxycucurbit-23-ene-3beta,7beta-diol (1), (23E)-cucurbita-5,23,25-triene-3beta,7beta-diol (2), (23E)-25-hydroxycucurbita-5,23-diene-3,7-dione (3), (23E)-cucurbita-5,23,25-triene-3,7-dione (4), and (23E)-5beta,19-epoxycucurbita-6,23-diene-3beta,25-diol (5), together with one known triterpene, (23E)-5beta,19-epoxy-25-methoxycucurbita-6,23-dien-3beta-ol (6), have been isolated from the methanol extract of the stems of Momordica charantia. The structures of the new compounds were elucidated by spectroscopic methods.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Molecular Structure
Momordica charantia / chemistry*
Nuclear Magnetic Resonance, Biomolecular
Plant Stems / chemistry
Plants, Medicinal / chemistry*
Taiwan
Triterpenes* / chemistry
Triterpenes* / classification
Triterpenes* / isolation & purification

Substances

Triterpenes