Abstract
An elderly woman with post-tuberculous stricture of the lower trachea and main bronchi underwent laser re-canalization, balloon dilation, and silicone stent insertion in the lower trachea and main bronchi. Subsequently she had recurrent dyspnea develop due to obstructing granulomas, which necessitated four endoscopic procedures in 2 years. The tracheal stent was removed and topical mitomycin-C was applied using saturated pledgets at a dose of 0.5 mg/mL for 2 minutes each over the lower trachea and both orifices of the main bronchi. Follow-up for 24 months showed no recurrence of symptoms. Bronchoscopy and spirometry performed at 2, 6, and 12 months showed resolution of the granulomas.
MeSH terms
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Administration, Topical
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Aged
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Bronchial Diseases / drug therapy*
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Bronchial Diseases / etiology
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Bronchial Diseases / surgery
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Bronchoscopy
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Catheterization
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Combined Modality Therapy
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Dyspnea / etiology
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Endoscopy
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Female
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Follow-Up Studies
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Forced Expiratory Volume
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Granuloma / drug therapy*
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Granuloma / etiology
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Granuloma / surgery
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Growth Inhibitors / administration & dosage*
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Growth Inhibitors / therapeutic use
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Humans
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Laser Therapy
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Mitomycin / administration & dosage*
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Mitomycin / therapeutic use
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Postoperative Complications / drug therapy*
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Postoperative Complications / surgery
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Stents
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Tracheal Diseases / drug therapy*
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Tracheal Diseases / etiology
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Tracheal Diseases / surgery
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Tracheal Stenosis / etiology
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Tracheal Stenosis / surgery
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Tuberculosis, Pulmonary / complications
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Vital Capacity
Substances
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Growth Inhibitors
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Mitomycin