Coronary artery calcium scoring with multislice computed tomography: in vitro assessment of a low tube voltage protocol

Invest Radiol. 2006 Sep;41(9):668-73. doi: 10.1097/01.rli.0000233324.09603.dd.

Abstract

Objectives: We sought to compare an 80-kVp coronary calcium scoring protocol with the standard protocol of 120 kVp in terms of accuracy and reproducibility and to assess its dose reduction potential.

Materials and method: An anthropomorphic heart phantom with calcium cylinders was scanned with different tube currents at 80 kVp and 120 kVp using a 16-slice multislice CT (MSCT) scanner. An adapted threshold for 80 kVp was calculated. Accuracy and reproducibility for calcium mass, volume, and Agatston score were analyzed using F-tests. The radiation doses needed to produce artifact-free images were determined.

Results: Accuracy (measurement errors: mass 120 kVp +4.6%, mass 80 kVp -6.9%, volume 120 kVp +78.8%, volume 80 kVp +58.2%) and reproducibility (F-tests: mass: P = 0.4998, volume: P = 0.9168, Agatston: P = 0.5422) were comparable at both tube voltages. Avoiding the appearance of artificial lesions, a CTDI(w,eff) of 10.7 mGy was needed at 120 kVp versus 4.6 mGy at 80 kVp (dose reduction of 57%).

Conclusions: Using an 80-kVp protocol in coronary calcium scoring, a relevant dose reduction is possible without compromising reproducibility and accuracy.

Publication types

  • Comparative Study

MeSH terms

  • Analysis of Variance
  • Calcinosis / diagnostic imaging*
  • Calcium / analysis*
  • Calibration
  • Phantoms, Imaging
  • ROC Curve
  • Radiation Dosage*
  • Reproducibility of Results
  • Tomography Scanners, X-Ray Computed
  • Tomography, X-Ray Computed / methods*
  • Tomography, X-Ray Computed / standards*

Substances

  • Calcium