Use of an immunochromatographic dipstick test for rapid detection of Trypanosoma cruzi in sera from animal reservoir hosts

J Clin Microbiol. 2006 Aug;44(8):3005-7. doi: 10.1128/JCM.00552-06.

Abstract

We evaluated an immunochromatographic dipstick test to detect Trypanosoma cruzi in canine serum samples from areas of endemicity (n = 141) and nonendemicity (n = 28) for Chagas' disease with known serological and xenodiagnostic test results. The dipstick test had a specificity of at least 94% and a sensitivity of at least 96%. The dipstick tested could become the first choice for screening purposes in disease surveillance or intervention programs.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chagas Disease / diagnosis
  • Chagas Disease / veterinary*
  • Chromatography, Affinity
  • Disease Reservoirs / microbiology*
  • Dog Diseases / diagnosis*
  • Dog Diseases / microbiology
  • Dogs
  • Humans
  • Immunologic Techniques*
  • Sensitivity and Specificity
  • Serum / parasitology*
  • Trypanosoma cruzi / immunology
  • Trypanosoma cruzi / isolation & purification*