History of aldosterone on its 50th birthday

J Nephrol. 2006 May-Jun:19 Suppl 10:S124-6.

Abstract

The paper describes the impact of mineralocorticoid substances on water regulation from Theophrastus (IV century B.C.) to Thomas Addison (1849). It also opens to the missed discovery of aldosterone of I.A. Macchi.

Publication types

  • Historical Article

MeSH terms

  • Aldosterone / chemistry
  • Aldosterone / history*
  • Aldosterone / isolation & purification
  • Aldosterone / physiology
  • Body Water / metabolism
  • History, 19th Century
  • History, 20th Century
  • Potassium / metabolism
  • Sodium / metabolism

Substances

  • Aldosterone
  • Sodium
  • Potassium