Abstract
Neurological manifestation is considered a rare complication of dengue infection. Neurological and cerebrospinal fluid (CSF) findings of 13 patients with dengue infection were studied. Seven patients had encephalitis, two had myelitis and four showed Guillain-Barré syndrome (GBS). No alteration in CSF was found from 57% of those with encephalitis. Patients with GBS and myelitis showed a CSF-blood barrier dysfunction. The differences in the CSF may be related to the location of the lesion and multiple mechanisms of the disease in the nervous system.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Adult
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Aged
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Cerebrospinal Fluid Proteins / analysis
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Cerebrospinal Fluid Proteins / immunology*
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Child
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Dengue / complications*
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Dengue Virus / immunology*
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Encephalitis, Viral / cerebrospinal fluid
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Encephalitis, Viral / diagnosis*
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Encephalitis, Viral / virology
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Female
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Guillain-Barre Syndrome / cerebrospinal fluid
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Guillain-Barre Syndrome / diagnosis*
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Guillain-Barre Syndrome / virology
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Humans
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Immunoglobulin M / cerebrospinal fluid
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Myelitis / cerebrospinal fluid
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Myelitis / diagnosis*
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Myelitis / virology
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Predictive Value of Tests
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Serotyping
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Spinal Cord / pathology
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Spinal Cord / physiopathology
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Spinal Cord / virology
Substances
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Cerebrospinal Fluid Proteins
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Immunoglobulin M