In99, an In100-related integron, its occurrence and prevalence in clinical Pseudomonas aeruginosa strains from a central region of Portugal

T Caetano; S Ferreira; A P Mondego; A Correia; S Mendo

doi:10.1017/S095026880600700X

In99, an In100-related integron, its occurrence and prevalence in clinical Pseudomonas aeruginosa strains from a central region of Portugal

Epidemiol Infect. 2007 Apr;135(3):502-4. doi: 10.1017/S095026880600700X. Epub 2006 Jul 26.

Authors

T Caetano¹, S Ferreira, A P Mondego, A Correia, S Mendo

Affiliation

¹ Departamento de Biologia, Universidade de Aveiro, Portugal.

Abstract

In99, a possible ancestor of In100, is a class 1 integron associated with carbenicillinase (blaPSE) and aminoglycoside resistance genes [aac(6')-Ib and aadA2]. In99 was present in 8 of 81 clinical isolates of Pseudomonas aeruginosa from unrelated patients collected in different years. The strains fell into two clonal groups and exhibited resistance to beta-lactams and aminoglycosides.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Drug Resistance, Bacterial / genetics
Electrophoresis, Gel, Pulsed-Field
Integrons*
Penicillinase / genetics
Portugal
Pseudomonas aeruginosa / drug effects
Pseudomonas aeruginosa / genetics*

Substances

Penicillinase