Povidone-iodine sclerotherapy is ineffective in the treatment of symptomatic renal cysts

J Endourol. 2006 Jun;20(6):402-4. doi: 10.1089/end.2006.20.402.

Abstract

Purpose: To evaluate the efficacy of povidone-iodine sclerotherapy after percutaneous drainage of simple renal cysts in the treatment of symptomatic patients.

Patients and methods: Sixteen patients with symptomatic renal cysts were treated by percutaneous drainage and injection of povidone-iodine solution. The cysts were drained by a nephrostomy tube catheter, and povidone- iodine injections were repeated every 24 hours for 3 days. All patients were followed up by ultrasound examination during a period ranging from 1 to 4 years (mean 1.8 years).

Results: Thirteen patients experienced recurrence of cysts, while complete resolution was observed in only three patients. Of the cysts that recurred, only partial resolution in cyst diameter was observed (from 3-10.5 cm to 2.4-8.6 cm). During the follow-up period, 12 of the 16 patients (75%) continued to have pain that necessitated additional treatments.

Conclusion: Povidone-iodine sclerotherapy is followed by a high rate of recurrence and is therefore not indicated for the treatment of symptomatic simple renal cysts.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Drainage
  • Female
  • Follow-Up Studies
  • Humans
  • Iodophors / administration & dosage*
  • Kidney Diseases, Cystic / diagnostic imaging
  • Kidney Diseases, Cystic / therapy*
  • Male
  • Middle Aged
  • Nephrostomy, Percutaneous
  • Povidone-Iodine / administration & dosage*
  • Recurrence
  • Sclerotherapy / methods*
  • Treatment Failure
  • Ultrasonography

Substances

  • Iodophors
  • Povidone-Iodine