Vortex configurations in superconducting films with regular arrays of antidots (holes) are calculated within the nonlinear Ginzburg-Landau theory. In addition to the well-established matching phenomena, we predict (i) the nucleation of giant-vortex states between the antidots, (ii) the combination of giant- and multivortices at rational matching fields, and (iii) for particular values of the vorticity, symmetry imposed creation of vortex-antivortex configurations.