Hemophagocytic lymphohistiocytosis complicating influenza A infection

Pediatrics. 2006 Jul;118(1):e216-9. doi: 10.1542/peds.2005-1861. Epub 2006 Jun 19.

Abstract

During the influenza A (H3N2) season of 2003-2004, several influenza-related complications and deaths were reported in children. Hemophagocytic lymphohistiocytosis complicating influenza A infection is very rare. We report a 3-year-old girl who presented with severe pneumonia and hemophagocytic lymphohistiocytosis associated with influenza A infection. Clinicians should be aware of hemophagocytic syndrome as a serious complication of influenza A infection.

Publication types

  • Case Reports
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Bone Marrow / pathology
  • Child, Preschool
  • Fatal Outcome
  • Female
  • Heart Arrest / etiology
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Influenza A Virus, H3N2 Subtype*
  • Influenza, Human / complications*
  • Lymphohistiocytosis, Hemophagocytic / etiology*
  • Lymphohistiocytosis, Hemophagocytic / pathology
  • Lymphohistiocytosis, Hemophagocytic / therapy

Substances

  • Immunoglobulins, Intravenous