New construction for transversal design

J Comput Biol. 2006 May;13(4):990-5. doi: 10.1089/cmb.2006.13.990.

Abstract

The study of gene functions requires the development of a DNA library of high quality through much of testing and screening. Pooling design is a mathematical tool to reduce the number of tests for DNA library screening. The transversal design is a special type of pooling design, which is good in implementation. In this paper, we present a new construction for transversal designs. We will also extend our construction to the error-tolerant case.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Computational Biology*
  • Data Interpretation, Statistical
  • Models, Statistical*
  • Research Design*
  • Sequence Analysis, DNA / statistics & numerical data*