[Incidence of methicillin-resistant Staphylococcus aureus strains (MRSA) and difficulties in treatment. Own experience]

Przegl Epidemiol. 2006;60(1):49-52.
[Article in Polish]

Abstract

The aim: To estimate the incidence of MRSA strains in hospitalized children, the analysis of antibiotic treatment necessity and its effectiveness.

Results: In 54 cases biological material obtained from hospitalized children revealed the culture of S. aureus, 22% of them were MRSA strains. Micro-organisms were cultured from throat swabs, faeces, purulent skin lesions, blood, cerebrospinal fluid. Antibiotic treatment was applied in 3 cases. Vancomycin (Edicin) was used as the first-choice option. Symptoms of drug intolerance was observed in all three cases after the first or the second dose, must have been immediately withdrawn.

Conclusions: MRSA strains are common in children population, they are not only nosocomial strains. Infections caused by S. aureus MRSA may result in life-threatening diseases. The generic formula of Vancomycin, that is used in Poland may cause serious side effects, which restricts narrow range of therapeutic options to eradicate MRSA strains.

Publication types

  • English Abstract

MeSH terms

  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / adverse effects
  • Child
  • Humans
  • Methicillin Resistance*
  • Poland
  • Species Specificity
  • Staphylococcal Infections / diagnosis
  • Staphylococcal Infections / drug therapy*
  • Staphylococcal Infections / microbiology*
  • Staphylococcus aureus / classification*
  • Treatment Outcome
  • Vancomycin / administration & dosage
  • Vancomycin / adverse effects

Substances

  • Anti-Bacterial Agents
  • Vancomycin