Supramolecular binding of protonated amines to a receptor microgel in aqueous medium

Alan Tominey; David Andrew; Lewis Oliphant; Georgina M Rosair; Juliette Dupré; Arno Kraft

doi:10.1039/b604393c

Supramolecular binding of protonated amines to a receptor microgel in aqueous medium

Chem Commun (Camb). 2006 Jun 21:(23):2492-4. doi: 10.1039/b604393c. Epub 2006 May 3.

Authors

Alan Tominey¹, David Andrew, Lewis Oliphant, Georgina M Rosair, Juliette Dupré, Arno Kraft

Affiliation

¹ Chemistry, School of Engineering and Physical Sciences, Heriot-Watt University, Edinburgh, UKEH14 4AS.

PMID: 16758026
DOI: 10.1039/b604393c

Abstract

Polyanionic microgels containing negatively charged tetrazole binding sites show supramolecular binding of various protonated amines (e.g. dibucaine and spermine) in a competitive aqueous medium at millimolar concentration.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Amines / chemistry*
Binding Sites
Gels / chemistry
Macromolecular Substances / chemistry*
Magnetic Resonance Spectroscopy / methods
Models, Molecular
Molecular Structure
Particle Size
Protons
Sensitivity and Specificity
Tetrazoles / chemistry*
Water / chemistry

Substances

Amines
Gels
Macromolecular Substances
Protons
Tetrazoles
Water
1H-tetrazole