Characterization of single nucleotide polymorphisms in sheep and their variation as evidence of selection

Anim Genet. 2006 Jun;37(3):290-2. doi: 10.1111/j.1365-2052.2006.01441.x.

Abstract

The discovery of SNPs was performed using animals from eight European sheep breeds. Eleven SNPs were further characterized using about 1,700 sheep belonging to 57 breeds. A method for the identification of loci that were likely subject to selection was applied; three of the 11 SNPs lying outside the 95% confidence region of the conditional joint distribution of F(ST) and mean heterozygosity were identified as outliers.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Female
  • Genotype
  • Heterozygote
  • Male
  • Polymorphism, Single Nucleotide*
  • Selection, Genetic*
  • Sequence Analysis, DNA
  • Sheep / genetics*