Effect of culture medium on the disk diffusion method for determining antifungal susceptibilities of dermatophytes

Antimicrob Agents Chemother. 2006 Jun;50(6):2222-4. doi: 10.1128/AAC.01443-05.

Abstract

We have evaluated a disk diffusion method to determine the activities of five drugs against 50 strains of dermatophytes and to assess the influence of the culture medium (antibiotic medium 3, high-resolution medium, and RPMI) on the inhibition zone diameters (IZD). There were no differences among the medium/drug combinations, except for itraconazole-RPMI, which showed the narrowest IZD.

Publication types

  • Comparative Study
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antifungal Agents / pharmacology*
  • Arthrodermataceae / drug effects*
  • Arthrodermataceae / genetics
  • Culture Media
  • Diffusion
  • Evaluation Studies as Topic
  • Itraconazole / pharmacology
  • Microbial Sensitivity Tests / methods
  • Species Specificity

Substances

  • Antifungal Agents
  • Culture Media
  • Itraconazole