Objective: To study the chemical constituents in roots of Heracleum rapula.
Method: The constituents were isolated by column chromatography on silica gel and ODS, and identified by spectroscopic methods.
Result: Nine compounds, osthol ( I ), bergapten (II), xanthotoxin (III), isopimpinellin (IV), imperatorin (V), isoimperatorin (VI), cnidilin (VII), phellopterin (VIII), rivulobirin A (IX) were isolated and identified.
Conclusion: Compounds VI, VII, VIII, IX were isolated from this plant for the first time.