Clostridium difficile ribotype 027, toxinotype III, the Netherlands

Ed J Kuijper; Renate J van den Berg; Sylvia Debast; Caroline E Visser; Dick Veenendaal; Annet Troelstra; Tjallie van der Kooi; Susan van den Hof; Daan W Notermans

doi:10.3201/eid1205.051350

Clostridium difficile ribotype 027, toxinotype III, the Netherlands

Emerg Infect Dis. 2006 May;12(5):827-30. doi: 10.3201/eid1205.051350.

Authors

Ed J Kuijper¹, Renate J van den Berg, Sylvia Debast, Caroline E Visser, Dick Veenendaal, Annet Troelstra, Tjallie van der Kooi, Susan van den Hof, Daan W Notermans

Affiliation

¹ Department of Medical Microbiology, National Reference Library for Clostridium difficile, Leiden University Medical Center, 2300 RC Leiden, the Netherlands. e.j.kuijper@lumc.nl

Abstract

Outbreaks due to Clostridium difficile polymerase chain reaction (PCR) ribotype 027, toxinotype III, were detected in 7 hospitals in the Netherlands from April 2005 to February 2006. One hospital experienced at the same time a second outbreak due to a toxin A-negative C. difficile PCR ribotype 017 toxinotype VIII strain. The outbreaks are difficult to control.

MeSH terms

Clostridioides difficile / classification
Clostridioides difficile / genetics*
Clostridioides difficile / isolation & purification
Cross Infection / prevention & control
Disease Outbreaks*
Enterocolitis, Pseudomembranous / epidemiology*
Enterocolitis, Pseudomembranous / microbiology*
Enterocolitis, Pseudomembranous / prevention & control
Enterotoxins* / biosynthesis
Enterotoxins* / genetics
Humans
Molecular Epidemiology
Netherlands / epidemiology
Polymerase Chain Reaction
Ribotyping

Substances

Enterotoxins