A new short synthesis of 10R-tuberculostearic acid and its enantiomer

Ieuan O Roberts; Mark S Baird

doi:10.1016/j.chemphyslip.2006.03.006

A new short synthesis of 10R-tuberculostearic acid and its enantiomer

Chem Phys Lipids. 2006 Jul;142(1-2):111-7. doi: 10.1016/j.chemphyslip.2006.03.006. Epub 2006 Mar 29.

Authors

Ieuan O Roberts¹, Mark S Baird

Affiliation

¹ Department of Chemistry, University of Wales, Bangor, Gwynedd, Wales LL57 2UW, UK.

PMID: 16690044
DOI: 10.1016/j.chemphyslip.2006.03.006

Abstract

Tuberculostearic acid (10R-methyloctadecanoic acid) and its 10S-enantiomer were synthesised by a chiral pool strategy, in four steps from citronellyl bromide.

MeSH terms

Monoterpenes / chemistry
Stearic Acids / chemical synthesis*
Stereoisomerism
Tuberculosis / diagnosis

Substances

Monoterpenes
Stearic Acids
tuberculostearic acid