Abstract
[reaction: see text] The synthesis of the highly strained 3-aza-[7]-paracyclophane core of haouamines A and B is based on a macrocyclization-aromatization protocol, allowing for a stepwise increase in ring strain and establishing the oxygenation pattern of the natural products.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
MeSH terms
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Aza Compounds / chemical synthesis*
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Aza Compounds / chemistry
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Crystallography, X-Ray
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Heterocyclic Compounds, 4 or More Rings / chemical synthesis*
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Heterocyclic Compounds, 4 or More Rings / chemistry
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Molecular Conformation
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Molecular Structure
Substances
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Aza Compounds
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Heterocyclic Compounds, 4 or More Rings
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haouamine A
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haouamine B