[Study on the process of inclusion volatile oil of Herba Schizonepetae with beta-cyclodextrin from xiao'er ganmaoshu granule]

Zhong Yao Cai. 2006 Feb;29(2):181-4.
[Article in Chinese]

Abstract

Objective: To study optimum inclusion process condition for volatile oil with beta-cyclodextrin (beta-CD).

Methods: The optimum preparation condition were investigated by orthogonal design. The influence of utilization beta-CD and oil, inclusion temperature and time were studied to determin the utilization ratio of volatile oil and oil-bearing rate.

Results: The optimum preparation conditions were established as: volatile oil: beta-CD was 1:10, the inclusion temperature was 60 degrees C and inclusion time was 3h.

Conclusion: The method is convenient and can he used for mass production.

Publication types

  • English Abstract

MeSH terms

  • Analysis of Variance
  • Drug Carriers
  • Drug Combinations
  • Drug Stability
  • Drugs, Chinese Herbal / analysis
  • Drugs, Chinese Herbal / chemistry*
  • Lamiaceae / chemistry*
  • Oils, Volatile* / analysis
  • Oils, Volatile* / chemistry
  • Oils, Volatile* / isolation & purification
  • Plants, Medicinal / chemistry
  • Technology, Pharmaceutical / methods*
  • Temperature
  • Time Factors
  • beta-Cyclodextrins* / chemistry

Substances

  • Drug Carriers
  • Drug Combinations
  • Drugs, Chinese Herbal
  • Oils, Volatile
  • beta-Cyclodextrins