The aim of the study was to evaluate the possibility of using a fluoride product included in a biodegradable membrane in remineralization of initial enamel carious lesions. The membrane has anti-bacterial, anti-inflammatory and remineralization properties, with a long-term effect. The efficiency of this treatment was assessed by measuring the surface of the demineralization area and its depth. The results proved that the use of this membrane in association with remineralization therapy of the initial enamel carious lesions increase the chances of success and represents a simple solution easily accepted by the patients.