Two cultivars significantly different in lycopene content were used for the study of inheritance pattern of lycopene content in fresh consumptive tomato fruit. Combination analysis of six generations proved that a major gene plus additive-dominance-epistasis polygenes dominate the inheritance of lycopene in fresh consumption tomato. The major gene heritability in B1, B2 and F2 was 6.85%, 34.78% and 58.33%, respectively, and the polygene heritability was 58.48%, 30.69% and 0, correspondingly.