Non-Newtonian blood flow in human right coronary arteries: transient simulations

J Biomech. 2006;39(6):1116-28. doi: 10.1016/j.jbiomech.2005.01.034.

Abstract

This study looks at pulsatile blood flow through four different right coronary arteries, which have been reconstructed from biplane angiograms. A non-Newtonian blood model (the Generalised Power Law), as well as the usual Newtonian model of blood viscosity, is used to study the wall shear stress in each of these arteries over the entire cardiac cycle. The difference between Newtonian and non-Newtonian blood models is also studied over the whole cardiac cycle using the recently generalised global non-Newtonian importance factor. In addition, the flow is studied by considering paths of massless particles introduced into the flow field. The study shows that, when studying the wall shear stress distribution for transient blood flow in arteries, the use of a Newtonian blood model is a reasonably good approximation. However, to study the flow within the artery in greater detail, a non-Newtonian model is more appropriate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Atrial Function, Right / physiology*
  • Blood Flow Velocity*
  • Computer Simulation*
  • Coronary Angiography
  • Coronary Vessels / physiology*
  • Humans
  • Models, Biological*
  • Shear Strength