Bladder filling variation during radiation treatment of prostate cancer: can the use of a bladder ultrasound scanner and biofeedback optimize bladder filling?

Int J Radiat Oncol Biol Phys. 2006 Jun 1;65(2):371-7. doi: 10.1016/j.ijrobp.2005.12.039. Epub 2006 Mar 15.

Abstract

Purpose: To investigate the use of a bladder ultrasound scanner in achieving a better reproducible bladder filling during irradiation of pelvic tumors, specifically prostate cancer.

Methods and materials: First, the accuracy of the bladder ultrasound scanner relative to computed tomography was validated in a group of 26 patients. Next, daily bladder volume variation was evaluated in a group of 18 patients. Another 16 patients participated in a biofeedback protocol, aiming at a more constant bladder volume. The last objective was to study correlations between prostate motion and bladder filling, by using electronic portal imaging device data on implanted gold markers.

Results: A strong correlation between bladder scanner volume and computed tomography volume (r = 0.95) was found. Daily bladder volume variation was very high (1 SD = 47.2%). Bladder filling and daily variation did not significantly differ between the control and the feedback group (47.2% and 40.1%, respectively). Furthermore, no linear correlations between bladder volume variation and prostate motion were found.

Conclusions: This study shows large variations in daily bladder volume. The use of a biofeedback protocol yields little reduction in bladder volume variation. Even so, the bladder scanner is an easy to use and accurate tool to register these variations.

Publication types

  • Validation Study

MeSH terms

  • Biofeedback, Psychology / physiology*
  • Humans
  • Male
  • Movement*
  • Prostate
  • Prostatic Neoplasms / diagnostic imaging
  • Prostatic Neoplasms / radiotherapy*
  • Regression Analysis
  • Statistics, Nonparametric
  • Ultrasonography
  • Urinary Bladder / anatomy & histology
  • Urinary Bladder / diagnostic imaging
  • Urinary Bladder / physiology*
  • Workload