Isolation of yessotoxin 32-O-[beta-L-arabinofuranosyl-(5'-->1'')-beta-L-arabinofuranoside] from Protoceratium reticulatum

Toxicon. 2006 Apr;47(5):510-6. doi: 10.1016/j.toxicon.2005.12.013. Epub 2006 Mar 10.

Abstract

Yessotoxin 32-O-[beta-L-arabinofuranosyl-(5'-->1'')-beta-L-arabinofuranoside] (3) was isolated from extracts of Protoceratium reticulatum during a large scale isolation of yessotoxin (1). The structure was characterized by mass spectrometry and NMR spectroscopy. Di-glycoside-3, along with the corresponding mono-glycoside (2) were detected in cultures of P. reticulatum originating from Europe and New Zealand, suggesting that production of arabinosides of 1 is a normal feature of this alga. Formation of multiply charged anions and fragmentation of 3 occurred much more readily than for 1 and 2 under the LC-MS conditions used in this study.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Models, Molecular
  • Molecular Structure
  • Mollusk Venoms / chemistry*
  • Mollusk Venoms / isolation & purification*
  • Oxocins / chemistry
  • Oxocins / isolation & purification*

Substances

  • Mollusk Venoms
  • Oxocins
  • yessotoxin 32-O-(beta-L-arabinofuranosyl-(5'-1'')-beta-L-arabinofuranoside), Protoceratium reticulatum