Detection of human papilloma virus (HPV) in laryngeal carcinoma tissue

H Wang; Y C Lin; X S Kang; G Z Li; J Li; B Y Liu; L J Qiao; K R Ma

Detection of human papilloma virus (HPV) in laryngeal carcinoma tissue

Chin Med J (Engl). 1991 Jun;104(6):523-5.

Authors

H Wang¹, Y C Lin, X S Kang, G Z Li, J Li, B Y Liu, L J Qiao, K R Ma

Affiliation

¹ Shanxi Cancer Institute, Taiyuan.

PMID: 1651831

Abstract

Using alpha-32P-dCTP labelled human papillomavirus type 16 DNA genome probe (cHPV 16 DNA, cloned and identified from a Chinese cervical invasive carcinoma), 3 HPV 16 genomic relative sequences were detected in 6 biopsies of laryngeal carcinoma. The results showed serious HPV infection in laryngeal carcinoma. This indicates that HPV infection may play an important pathogenetic role in cancer development.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Blotting, Southern
Carcinoma / microbiology*
DNA Probes, HPV
DNA, Viral / analysis*
Humans
Laryngeal Neoplasms / microbiology*
Papillomaviridae / isolation & purification*
Tumor Virus Infections*

Substances

DNA Probes, HPV
DNA, Viral