[Methods of diagnosis and differentiation of plague pathogen: approaches to detection of atypical strains of Yersinia pestis by molecular biology. Part I]

Mol Gen Mikrobiol Virusol. 2006:(1):3-6.
[Article in Russian]

Abstract

A review of data on the modern methods of detection of typical and atypical strains of the plague agent Y. pestis is given. The history of the development of the molecular-biological tests for the differentiation of Y. pestis from the related microorganisms is presented. The problems facing investigators during the development of these tests are discussed.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Animals
  • Bacteriological Techniques / history
  • DNA Primers
  • DNA, Bacterial / genetics
  • History, 20th Century
  • History, 21st Century
  • Humans
  • Plague / microbiology
  • Plasmids / genetics
  • Polymerase Chain Reaction / methods
  • Ribotyping
  • Species Specificity
  • Yersinia pestis / classification*
  • Yersinia pestis / genetics
  • Yersinia pestis / isolation & purification*

Substances

  • DNA Primers
  • DNA, Bacterial