Abstract
A review of data on the modern methods of detection of typical and atypical strains of the plague agent Y. pestis is given. The history of the development of the molecular-biological tests for the differentiation of Y. pestis from the related microorganisms is presented. The problems facing investigators during the development of these tests are discussed.
Publication types
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Historical Article
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Review
MeSH terms
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Animals
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Bacteriological Techniques / history
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DNA Primers
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DNA, Bacterial / genetics
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History, 20th Century
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History, 21st Century
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Humans
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Plague / microbiology
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Plasmids / genetics
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Polymerase Chain Reaction / methods
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Ribotyping
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Species Specificity
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Yersinia pestis / classification*
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Yersinia pestis / genetics
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Yersinia pestis / isolation & purification*
Substances
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DNA Primers
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DNA, Bacterial