Influence of age on outcome of psychological treatments in first-episode psychosis

Br J Psychiatry. 2006 Mar:188:250-4. doi: 10.1192/bjp.188.3.250.

Abstract

Background: Psychological treatments have been shown to be effective in patients with psychosis. However, the studies published to date have included participants across wide age ranges, so few conclusions can be reached about the effectiveness of such treatments in relation to age.

Aims: To evaluate outcomes by age in a randomised controlled trial designed to evaluate the effectiveness of cognitive-behavioural therapy (CBT), supportive counselling and treatment as usual.

Method: Outcomes were evaluated in terms of symptoms, social functioning, insight and therapeutic alliance according to age at 3- and 18-month follow-up.

Results: Younger participants responded better to supportive counselling than to treatment as usual and CBTover 3 months. Older participants responded better to CBT than to supportive counselling over 18 months. Younger participants showed a greater increase in insight after CBT compared with treatment as usual and supportive counselling, and were more difficult to engage in therapy.

Conclusions: Young people may have different needs with regard to engagement in psychological treatments. Treatment providers need to take age-specific factors into account.

Publication types

  • Multicenter Study
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Antipsychotic Agents / therapeutic use
  • Cognitive Behavioral Therapy*
  • Combined Modality Therapy
  • Counseling
  • Female
  • Follow-Up Studies
  • Humans
  • Interpersonal Relations
  • Male
  • Physician-Patient Relations
  • Psychiatric Status Rating Scales
  • Psychotic Disorders / psychology
  • Psychotic Disorders / therapy*
  • Single-Blind Method
  • Treatment Outcome

Substances

  • Antipsychotic Agents