Antibacterial and cytotoxic xanthones from the roots of Cratoxylum formosum

Sompong Boonsri; Chatchanok Karalai; Chanita Ponglimanont; Akkharawit Kanjana-opas; Kan Chantrapromma

doi:10.1016/j.phytochem.2006.01.007

Antibacterial and cytotoxic xanthones from the roots of Cratoxylum formosum

Phytochemistry. 2006 Apr;67(7):723-7. doi: 10.1016/j.phytochem.2006.01.007. Epub 2006 Feb 21.

Authors

Sompong Boonsri¹, Chatchanok Karalai, Chanita Ponglimanont, Akkharawit Kanjana-opas, Kan Chantrapromma

Affiliation

¹ Department of Chemistry, Faculty of Science, Prince of Songkla University, Hat-Yai, Songkhla 90112, Thailand.

PMID: 16494905
DOI: 10.1016/j.phytochem.2006.01.007

Abstract

Chemical investigation of the roots of Cratoxylum formosum has resulted in the isolation and characterization of xanthones: three new, named formoxanthone A-C and three known together with three known anthraquinones. Their structures were established on the basis of analysis of spectroscopic evidence. In addition, antibacterial and cytotoxic activities of the isolates were also evaluated.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anthraquinones / chemistry
Anthraquinones / isolation & purification
Anthraquinones / pharmacology
Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / isolation & purification
Anti-Bacterial Agents / pharmacology*
Antineoplastic Agents, Phytogenic / chemistry
Antineoplastic Agents, Phytogenic / isolation & purification
Antineoplastic Agents, Phytogenic / pharmacology
Clusiaceae / chemistry*
Fungi / drug effects*
Humans
Microbial Sensitivity Tests
Plant Extracts / chemistry
Plant Extracts / pharmacology
Plant Roots / chemistry*
Plants, Medicinal
Toxicity Tests
Tumor Cells, Cultured
Xanthones / chemistry
Xanthones / isolation & purification
Xanthones / pharmacology*

Substances

Anthraquinones
Anti-Bacterial Agents
Antineoplastic Agents, Phytogenic
Plant Extracts
Xanthones
formoxanthone A
formoxanthone B
formoxanthone C